INSTRUMENTS AND TECHNIQUES
Thermodynamic and Kinetic analysis
DIFFERENTIAL SCANNING CALORIMETER (DSC)
Nano DSC (TA instruments)
The Nano DSC has the versatility and precision for characterizing molecular stability, determining high affinity ligand binding and deconvoluting multi-domain structures. The Nano DSC is designed for ultra-sensitive measure of heat absorbed or released by dilute in-solution bio-molecules as they are heated or cooled.
Fluorolog-3 spectrofluorimeter (Horiba Scientific)
The instrument is fitted with a double monochromator and T-Box Sample Module, allowing for steady-state fluorescence, fluorescence anisotropy, and kinetic measurements.
FLUORESCENCE KINETIC STUDIES
SX-20 Stopped Flow Spectrometer (Applied Photophysics)
Speed together with a choice of mixing and detection options, offer maximum productivity in steady-state and kinetic studies. A comprehensive range of accessories, including sequential mixing, fluorescence polarization, and photodiode array detection.
INVENIO ATR-FTIR Spectrometer (Bruker)
efficient beam path design and precise optics, controlled by state-of-the-art SoC electronics, the INVENIO provides peak performance and reveals the smallest spectral details. The attenuated total reflection (ATR) attachment allows for minimizing background absorption for a more accurate and sensitive detection.
MODULAR FLUORESCENCE LIFETIME SPECTROMETER
FluoTime 200 (PicoQuant)
The FluoTime 200 spectrometer is a high performance fluorescence lifetime system featuring modular construction, single photon timing sensitivity and research flexibility. It contains the complete optics and electronics for recording fluorescence decays by means of Time-Correlated Single Photon Counting (TCSPC) and/or Multi-Channel Scaling (MCS).
TEMPERATURE JUMP KINETICS
TJ-64 T-jump (TgK Scientific)
The system has a thermostated cell coupled directly to an optical system with absorption and fluorescence detection options. The signal detection system incorporates fast response amplifiers and signal conditioning electronics. Data acquisition and processing is handled by Kinetic Studio, which allows the acquisition of data on linear and logarithmic time bases together with display and analysis.